Used For

Anesthesia

The central actions of benzodiazepines are mediated through an enhancement of the GABAergic neurotransmission at inhibitory synapeses. In the presence of benzodiazepines, the affinity of the GABA receptor for the neurotransmitter is enhanced through positive allosteric modulation resulting in an increased action of released GABA on the postsynaptic transmembrance chloride ion flux.

Fluctuations in vital signs including decreased respiratory effects, variation in blood pressure and pulse rate are the most frequently seen findings. Laryngospasm, bronchospasm, dyspnoea, hyperventilation and airway obstruction.Premature ventricular contraction, vasovagal episode and tachycardia.Retrograde amnesia, euphoria, confusion, nervousness, restlessness, nightmares dysphonia and paresthesia.Blurred vision, diplopia, nystagamus, visual disturbances, blocked ears, loss of balance and light headedness.Headache, hiccough, nausea, vomiting, yawning, lethargy, weakness and faint feeling.