It is used for the treatment of Parkinson’s disease and syndrome.

It can cause Chest pain, asthenia, Cardiac irregularities, hypotension, orthostatic effects including orthostatic hypotension, hypertension, syncope, phlebitis, palpitation, Dark saliva, gastrointestinal bleeding, development of duodenal ulcer, anorexia, vomiting, diarrhea, constipation, dyspepsia, dry mouth, taste alterations.

Hypersensitivity to the drug and Use of the drug in patients below the age of 18 is not recommended. Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with SINEMET