Prevention of angina pectoris caused by coronary artery disease

Abdominal pain, arm, back or jaw pain, black tarry stool, blurred vision, chills, cold sweats, cough

Hypersensitivity to organic nitrates.PDE-5 inhibitors (eg, avanafil, sildenafil, tadalafil, or vardenafil); concomitant use can cause severe hypotension, syncope, or myocardial ischemia. Concomitant administration with guanylate stimulator riociguat (may cause hypotension)